Cancer Transcriptome Atlas

Curated Content for Cancer Biology

The GeoMx Cancer Transcriptome Atlas (CTA) is designed for comprehensive profiling of the tumor biology, tumor microenvironment, and the immune response. Profile the RNA expression over 1,800 genes simultaneously with spatial resolution in any region of interest from a single tissue section using the GeoMx Digital Spatial Profiler.



Product Highlights

  • Comprehensive RNA content designed for cancer biology research
    • Expansive coverage of the immune response, tissue microenvironment, tumor biology, and genes from clinically relevant genes sets such as tumor inflammation
    • Includes genes for the Tumor Inflammation Signature, PAM50 and other clinical signatures
    • Over 100 pathways to explore all aspects of cancer and tumor biology
    • Request CTA Product Bulletin
  • Compatible with RNAscope® and antibody visualization markers
  • Supplement with up to 60 additional targets of interest
  • For use with next-generation sequencer (NGS) readout and compatible with DSP Data Center


Comprehensively Annotated Pathways in the CTA

Adaptive Immunity   Cell Function   Signaling Pathways
T cells B cells   Apoptosis   AMPK Signaling
TCR & BCR Signaling   Autophagy   Androgen Signaling
Cancer Antigens   Cell Adhesion & Motility   EGFR Signaling
MHC Class I & II Antigen Presentation   Cell Cycle   ERBB2 Signaling
T-cell Checkpoints   Cilium Assembly   Estrogen Signaling
TH1, TH2, TH9, Th17, and Treg Differentiation   Differentiation   FGFR Signaling
    DNA Damage Repair   FoxO Signaling
Innate Immunity   EMT   GPCR Signaling
Complement System   Endocytosis   Hedgehog Signaling
Dendritic Cells   Epigenetic Modification   HIF1 Signaling
DNA & RNA Sensing   Immortality & Stemness   Insulin Signaling
Glycan Sensing   Ion Transport   JAK-STAT Signaling
Host Defense Peptides   Lysosome   MAPK Signaling
Inflammasomes   Oxidative Stress   MET Signaling
Myeloid Inflammation   Phagocytosis   mTOR Signaling
Neutrophil Degranulation   Proteotoxic Stress   Myc
NK Activity   RNA Processing   NO Signaling
NLR Signaling   Senescence   Notch Signaling
RAGE Signaling       p53 Signaling
TLR Signaling   Metabolism   PDGF Signaling
    Amino Acid Synthesis & Transport   PI3K-Akt Signaling
Immune Response   Arginine & Glutamine Metabolism   PPAR Signaling
Chemokine Signaling   Fatty Acid Oxidation & Synthesis   Purinergic Signaling
Cytotoxicity   Glycolysis & Glucose Transport   Retinoic Acid Signaling
IL-1, IL-2, IL-6 & IL-17 Signaling   Glycosylation   TGF-beta Signaling
Immune Exhaustion   IDH1/2   VEGF Signaling
Interferon Response Genes   Lipid Metabolism   Wnt Signaling
Lymphocyte Regulation & Trafficking   Mitochondrial Metabolism / TCA    
NF-kB Signaling   Nucleotide Synthesis   Physiology & Disease
Other Interleukin Signaling   Pentose Phosphate   Angiotensin System
Prostaglandin Inflammation   Tryptophan & Kynurenine Metabolism   Circadian Clock
TNF Signaling   Vitamin & Cofactor Metabolism   Drug Resistance
Type I, II, & III Interferon Signaling       Glioma
        Matrix Remodeling and Metastasis
        Neuroendocrine Function
        Prostate Cancer


For Research Use Only. Not for use in diagnostic procedures.